|
Esophageal Neoplasms
|
0.310 |
Biomarker
|
group |
CTD_human |
The analyses pointed out the potential importance of CXCL2, and monitoring CXCL2 with quantitative videomicroscopy indicated that its biologic activity was silenced in OE21 esophageal cancer cells.
|
21509778 |
2011 |
|
Esophageal Neoplasms
|
0.310 |
AlteredExpression
|
group |
BEFREE |
The analyses pointed out the potential importance of CXCL2, and monitoring CXCL2 with quantitative videomicroscopy indicated that its biologic activity was silenced in OE21 esophageal cancer cells.
|
21509778 |
2011 |
|
Mammary Neoplasms
|
0.310 |
Biomarker
|
group |
LHGDN |
Curcumin downregulates the inflammatory cytokines CXCL1 and -2 in breast cancer cells via NFkappaB.
|
17999991 |
2008 |
|
Mammary Neoplasms
|
0.310 |
Biomarker
|
group |
CTD_human |
ERE-independent ERalpha target genes differentially expressed in human breast tumors.
|
16298037 |
2005 |
|
Hypertensive disease
|
0.300 |
Biomarker
|
group |
CTD_human |
Vascular and thrombogenic effects of pulmonary exposure to Libby amphibole.
|
22352330 |
2012 |
|
Dermatologic disorders
|
0.300 |
Biomarker
|
group |
CTD_human |
Gene expression profiles in peripheral lymphocytes by arsenic exposure and skin lesion status in a Bangladeshi population.
|
16835338 |
2006 |
|
Lung diseases
|
0.210 |
Biomarker
|
group |
BEFREE |
Given the bioactivities of MIP-1 alpha and beta and MIP-2 and the recent studies demonstrating their association with lung inflammation, it is likely these chemokines play a significant role in respiratory tract defenses and may contribute to the pathogenesis of inflammatory lung disease.
|
7882902 |
1995 |
|
Lung diseases
|
0.210 |
Biomarker
|
group |
RGD |
Protection against sepsis-induced lung injury by selective inhibition of protein kinase C-δ (δ-PKC).
|
20724665 |
2011 |
|
Lung diseases
|
0.210 |
Biomarker
|
group |
RGD |
Superimposed gastric aspiration increases the severity of inflammation and permeability injury in a rat model of lung contusion.
|
19515386 |
2009 |
|
Lung diseases
|
0.210 |
Biomarker
|
group |
RGD |
Apocynin attenuates ventilator-induced lung injury in an isolated and perfused rat lung model.
|
21618001 |
2011 |
|
Lung diseases
|
0.210 |
Biomarker
|
group |
RGD |
Akt pathway is required for oestrogen-mediated attenuation of lung injury in a rodent model of cerulein-induced acute pancreatitis.
|
20709317 |
2011 |
|
Lung diseases
|
0.210 |
Biomarker
|
group |
RGD |
Platonin mitigates acute lung injury induced by bilateral lower limb ischemia-reperfusion in rats.
|
20472255 |
2011 |
|
Pneumonia, Bacterial
|
0.200 |
Biomarker
|
group |
RGD |
Role of cytokine-induced neutrophil chemoattractant-2 (CINC-2) alpha in a rat model of chronic bronchopulmonary infections with Pseudomonas aeruginosa.
|
11052817 |
2000 |
|
Alcoholic Liver Diseases
|
0.200 |
Biomarker
|
group |
RGD |
Activation of nuclear factor kappa B and cytokine imbalance in experimental alcoholic liver disease in the rat.
|
10498645 |
1999 |
|
Coronavirus Infections
|
0.200 |
Biomarker
|
group |
RGD |
Rat coronaviruses infect rat alveolar type I epithelial cells and induce expression of CXC chemokines.
|
17804032 |
2007 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Evidence of biological HP-NAP activity was observed 24 hours after treatment with neutrophil infiltration in tumors and an increase of proinflammatory cytokines such as tumor necrosis factor (TNF)-α and MIP2-α in the systemic circulation.
|
23817216 |
2013 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
The results indicated that LPS upregulated a series of pro-inflammatory cytokines and theophylline significantly attenuated the expression levels of pro-inflammatory cytokines tumor necrosis factor‑α, macrophage inflammatory protein (MIP)-1α and MIP-2, and markedly elevated the production of tumor growth factor (TGF)-β family members TGF-β1, TGF-β2 and TGF-β3, which are anti‑inflammatory cytokines.
|
24788885 |
2014 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Addition of MMM to colon tumors <i>in vivo</i> significantly enhances tumor growth in control tumors and restores tumor growth in the presence of MK2 inhibition.
|
30298062 |
2018 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Analysis of immune cells revealed that CXCR2 ligands (CXCL1, CXCL 2 and CXCL5) expressed by TNFα-activated MSCs efficiently recruited CXCR2<sup>+</sup> neutrophils into tumor.
|
27375023 |
2017 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
Chemokine (C-X-C motif) ligand 1 and CXCL2 produced by tumor promote the generation of monocytic myeloid-derived suppressor cells.
|
30259595 |
2018 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
To study the effect of localised secretion of chemokines on tumour growth, the genes for human (hu) interleukin 8 (IL-8), hu-MCP-1 (MCAF), hu-MIP-1 alpha (LD78), murine (mu)-MCP-1 (JE), mu-MIP-1 alpha or mu-MIP-2 were introduced, via mammalian expression vectors, into Chinese hamster ovary (CHO) cells, and the ability of transfected cells to form tumours in vivo was evaluated.
|
7669585 |
1995 |
|
Neoplasms
|
0.100 |
AlteredExpression
|
group |
BEFREE |
Tumor cell growth in Emilin2 null mice was impaired as well as the expression of MIP-2.
|
29483644 |
2018 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
In animal studies, we found that overexpressing CXCL2 by lentivirus also apparently inhibited the size and weight of subcutaneous tumours in nude mice.
|
30293547 |
2018 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
The incidence of the tumor reached about 40% when the rats were 12 months old. mRNAs of both pX and host genes Gro and MIP-2, which are granulocyte chemoattractants of the interleukin 8 family, were highly expressed in the tumor tissue.
|
7780962 |
1995 |
|
Neoplasms
|
0.100 |
Biomarker
|
group |
BEFREE |
CXCL2 secreted from TAM-like macrophages plays an important role in tumour invasiveness.
|
27425378 |
2016 |